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. 2021 Jun 30;9(5):1378–1388. doi: 10.1016/j.gendis.2021.06.002

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — Expression of DEGs. (A) The expression of TRIB1 according to the mRNA sequencing. The statistical significance between healthy control subjects and VKH patients with active uveitis before treatment was examined by independent Mann Whitney test (P = 0.004). The statistical significance between VKH patients before and after treatment was examined by Wilcoxon matched-pairs signed rank test (P = 0.016). The statistical significance between healthy control subjects and VKH patients after treatment was examined by independent Mann Whitney test (P = 0.535). (B) The expression of SGK1 by RT-qRCR. The bars indicate median with interquartile range. The statistical significance between healthy control subjects and VKH patients with active uveitis before treatment was examined by independent Mann Whitney test (P = 0.011). (C) The expression of TRIB1 by RT-qRCR. The bars indicate median with standard deviation. The statistical significance between healthy control subjects and VKH patients with active uveitis before treatment was examined by t test (P = 0.035). ns, no statistical significance. HC, healthy control. Va, VKH patients with active uveitis before treatment. Vt, VKH patients after prednisone combined with cyclosporine treatment.