Fig. 4.

Role of Nox4 in normal steady-state hematopoiesis. a Peripheral blood counts; white blood count (WBC), red blood count (RBC), hematocrit (HCT) level, hemoglobin (HGB) level, and platelet count (PLT) after conditional deletion of Nox4 during normal steady-state hematopoiesis through 20 weeks. b Immunophenotypic quantification of HSPCs as indicated in Fig. 3d. c–e Immunophenotypic quantification of mature myeloid (Gr-1⁺ or Mac1⁺), B-lymphoid (CD19⁺), and T-lymphoid (CD3⁺) cells in c BM, d peripheral blood and e spleen. Error bars indicate the standard deviation. (*P < 0.05, by two-tailed t-test)