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. 2022 Mar 14;269(8):4270–4280. doi: 10.1007/s00415-022-11055-5

Table 2.

CSF biomarkers in Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), and Alzheimer’s disease (AD) groups (86 patients)

SCD MCI AD
N° 23 N° 41 N° 22
Aβ1–42 1077.61 (± 410.34)* 888.10 (± 452.62)° 553.73 (± 127.82)*°
Aβ1–42/1–40 0.088 (± 0.028)^ç 0.065 (± 0.029)^ 0.048 (± 0.011)ç
p-tau 68.57 (± 110.18)λ 78.59 (± 41.02)ψ 113.19 (± 67.79)λ ψ
t-tau 381.29 (± 227.90)& 510.14 (± 264.81)§ 814.72 (± 375.32)& §

Values are reported as mean and standard deviation. Statistically significantly different values between the groups are reported as underlined character. *p < 0.001; °p = 0.004; ^p = 0.005; çp < 0.001; λp = 0.012; ψp = 0.018; &p < 0.001; §p < 0.001