Table 3.
Uni- and multivariable comparisons between seizing ICU patients with and without seizure recurrence
| Associations | Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|---|
| Potential associations in all ICU patients (i.e., variables being significant in Table 2) |
OR for recurrent seizures |
95% CI | p value* | OR for recurrent seizures |
95% CI | p value** | |
| Seizures reported to be focal to bilateral | 0.41 | 0.22–0.77 | 0.005 | 0.60 | 0.30–1.21 | 0.154 | |
| Epilepsy as presumed etiology | 2.55 | 1.06–6.11 | 0.036 | 2.25 | 0.83–6.06 | 0.110 | |
| Metabolic derangement as presumed etiology (other than acidosis) | 0.44 | 0.22–0.85 | 0.015 | 0.52 | 0.24–1.09 | 0.084 | |
| APACHE II (per increasing unit) | 0.93 | 0.89–0.97 | 0.002 | 0.97 | 0.92–1.04 | 0.396 | |
| SOFA (per increasing unit) | 0.88 | 0.80–0.97 | 0.009 | 0.98 | 0.86–1.11 | 0.707 | |
| Acidosis at seizure onset (per decreasing pH) | 0.33 | 0.17–0.64 | 0.001 | 0.43 | 0.20–0.94 | 0.035 | |
| Previous emergency operation | 0.48 | 0.26–0.92 | 0.026 | 0.48 | 0.24–0.97 | 0.041 | |
OR odds ratio, CI confidence interval, APACHE II acute physiology and chronic health evaluation II, SOFA sequential organ failure assessment, ICU intensive care unit
Bold font indicates statistical significance
*Logistic regression analyses
**Hosmer–Lemeshow goodness-of-fit test: Chi-squared 3.26, p = 0.917 indicating adequate model fit