Fig. 5.

a Normalized LCK expression in the different cohorts (as explained in Fig. 2b). b Altered isoform expression of LCK using JunctionSeq showing estimated normalized mean read-pair count for each exon and splice junctions in the different cohorts (left) as well as for the whole LCK gene (right). The significantly alternatively spliced feature, E016 (pink), corresponds to chr1:32274818–32274992 (GRCh38). The alternative LCK transcripts used in the JunctionSeq analysis are shown below with their corresponding ENSEMBL identifiers