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. 2022 Jul 14;15(7):100667. doi: 10.1016/j.waojou.2022.100667

Table 2.

Association between characteristics of participants and allergic sensitization trajectory by multivariate multinomial logistic regression (n = 396).


Early food and mite sensitization

Late mite sensitization

AOR (95% CI) P AOR (95% CI) P
Sex
 Male Ref Ref
 Female 0.72 (0.40–1.32) 0.294 0.58 (0.35–0.96) 0.033a
Ethnicity 0.532 0.121
 Chinese Ref Ref
 Malay 1.02 (0.41–2.49) 0.971 1.26 (0.63–2.52) 0.521
 Indian 0.54 (0.18–1.63) 0.273 0.45 (0.18–1.09) 0.078
Maternal education level
 Secondary school education or less Ref Ref
 Post-secondary and higher 1.22 (0.53–2.78) 0.642 1.61 (0.85–3.03) 0.142
Family history of allergy 1.27 (0.68–2.37) 0.458 1.08 (0.65–1.80) 0.775
Maternal plasma Vitamin D3 0.730 0.530
 Deficient Ref Ref
 Insufficient 0.93 (0.30–2.89) 0.905 0.82 (0.34–1.99) 0.658
 Sufficient 1.24 (0.42–3.62) 0.697 1.16 (0.50–2.66) 0.735
Maternal age in years 1.03 (0.96–1.10) 0.453 0.97 (0.92–1.03) 0.365
Parity 0.981 0.444
 0 Ref Ref
 1 0.97 (0.47–1.97) 0.924 1.35 (0.74–2.46) 0.326
 ≥2 0.91 (0.35–2.36) 0.844 1.55 (0.74–3.25) 0.240
Gestational age in weeks 1.01 (0.81–1.27) 0.915 1.09 (0.89–1.33) 0.401
Tobacco exposure during pregnancy 0.85 (0.39–1.85) 0.688 1.23 (0.68–2.22) 0.490
Mode of delivery
 Vaginal delivery Ref Ref
 Cesarean section 0.72 (0.37–1.42) 0.348 0.54 (0.30–0.98) 0.042a
Breastfeeding 0.026 0.360
 Mainly breastfeeding Ref Ref
 Mixed feeding 2.43 (0.96–6.16) 0.061 1.47 (0.71–3.04) 0.305
 Mainly formula feeding 1.03 (0.36–2.98) 0.952 1.01 (0.46–2.21) 0.988
Eczema in early life by 6 months 4.67 (1.78–12.28) 0.002a 3.40 (1.38–8.42) 0.008a
Cat ownership by 1 year 1.51 (0.43–5.35) 0.525 0.85 (0.27–2.61) 0.771
Dog ownership by 1 year 0.13 (0.02–1.08) 0.059 0.97 (0.39–2.41) 0.945
Childcare attendance by 1 year 2.12 (0.92–4.90) 0.078 2.01 (0.97–4.15) 0.059

AOR, adjusted odds ratio; CI, confidence interval.

No/low sensitization trajectory was the baseline group for odds.

a

p value that was significant