Table 1.
Clinical, anthropometric and electrocardiographic data.
| LVEF < 0.40 (N = 32) | LVEF ≥ 0.40 and < 0.50 (N = 10) | LVEF ≥ 0.50 (N = 30) | p | |
|---|---|---|---|---|
| Gender | Male = 19 (59%) | Male = 7 (70%) | Male = 14 (47%) | 0,71 |
| Mean Age ± SD (years) | 53.6 ± 9,1 | 48.0 ± 8.1 | 54.0 ± 9.4 | 0.17 |
| Weight (Kg) | 67.0 ± 9,9 | 71.8 ± 12.0 | 68.8 ± 10.9 | 0.45 |
| Height (cm) | 163.9 ± 7,7 | 164.1 ± 7.5 | 164.3 ± 7.2 | 0.98 |
| BSA (g/m2) | 1.73 ± 0.14 | 1.78 ± 0.18 | 1.75 ± 0.15 | 0.83 |
| Medical treatment | ||||
| ACEi | N = 18 (56%) | N = 7 (70%) | N = 5 (17%) | 0.003 |
| ARBs | N = 11 (21%) | N = 3 (30%) | N = 5 (17%) | 0.094 |
| Beta blockers | N = 31(97%) | N = 10 (100%) | N = 7 (23%) | < 0.001 |
| Furosemide | N = 22 (69%) | N = 3 (30%) | N = 0 | < 0.001 |
| Thiazide diuretics | N = 11 (21%) | N = 1 (10%) | N = 3 (10%) | 0.005 |
| Spironolactone | N = 19 (59%) | N = 7 (70%) | N = 0 | < 0.001 |
| Digoxin | N = 4 (13%) | N = 1 (10%) | N = 0 | 0.152 |
| Nitrates | N = 5 (16%) | N = 0 | N = 0 | 0.002 |
| Hydralazine | N = 3 (9%) | N = 0 | N = 0 | 0.109 |
| Warfarin | N = 9 (28%) | N = 1 (10%) | N = 0 | 0.82 |
| Amiodarone | N = 3 (9%) | N = 3 (30%) | N = 2 (7%) | 0.62 |
| Functional class (NYHA) | ||||
| I | N = 13 (41%) | N = 5 (50%) | N = 25 (83%) | < 0.001 |
| II | N = 13 (41%) | N = 4 (40%) | N = 5 (17%) | |
| III | N = 5 (16%) | N = 1 (10%) | N = 0 | |
| IV | N = 1 (2%) | N = 0 | N = 0 | |
| SBP (mmHg) | 111.0 ± 12.3 | 116.2 ± 9.8 | 120.6 ± 12.7 | 0.002 |
| DBP (mmHg) | 71.2 ± 9.1 | 77.6 ± 7.2 | 78.1 ± 7.2 | 0.004 |
| PR interval (ms) | 0.18 ± 0.06 | 0.16 ± 0.03 | 0.17 ± 0.02 | 0.44 |
| QRS interval (ms) | 0.13 ± 0.03 | 0.12 ± 0.03 | 0.11 ± 0.03 | 0.06 |
| Morfology | ||||
| LBBB | N = 4 (13%) | N = 0 | N = 2 (7%) | 0.33 |
| RBBB | N = 12 (32%) | N = 3 (30%) | N = 2 (7%) | 0.42 |
| RBBB and left anterior fascicular block | N = 2 (6%) | N = 1 (10%) | N = 5 (17%) | 0.32 |
| Holter | ||||
| NSVT | N = 12 (38%) | N = 4 (40%) | N = 1 (3%) | 0.05 |
| Creatinine (mg/dl) | 1.08 ± 0.27 | 0.98 ± 0.14 | 0.92 ± 0.2 | 0.03 |
| Urea (mg/dl) | 43.8 ± 15.6 | 35.7 ± 10.2 | 34.5 ± 11.4 | 0.02 |
Significant values are in bold.
*LVEF Left ventricular ejection fraction, SD Standard deviation, BSA Body surface area, SAH Systemic arterial hypertension, ACEi Angiotensin-converting-enzyme inhibitors, ARBs Angiotensin receptor blockers, ASA acetylsalicylic acid, NYHA New York Heart Association, SBP systolic blood pressure, DBP Diastolic blood pressure, LBBB Left bundle brunch block, RBBB Right bundle brunch block, NSVT Non-sustained ventricular tachycardia, BNP Brain natriuretic peptide.