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. 2022 Jul 18;12:12237. doi: 10.1038/s41598-022-16379-w

Table 2.

Conventional echocardiographic parameters.

LVEF < 0.40 (N = 32) LVEF ≥ 0.40 and < 0.50 (N = 10) LVEF ≥ 0.50 (N = 30) p
Aorta (mm) 31.4 ± 3.4 34.1 ± 4.1 32.3 ± 3.2 0.09
Left atrium (mm) 43.7 ± 7.4 40.7 ± 6.8 37.4 ± 5.0 0.001
Left atrium volume indexed (ml/m2) 49.5 ± 15.9 40.4 ± 11.2 30.6 ± 7.6  < 0.001
RA area (cm2) 18.9 ± 7.4 15.5 ± 2.5 15.3 ± 2.7 0.02
RA volume (cm3) 58.2 ± 39.0 42.2 ± 10.1 38.1 ± 12.0 0.01
RV basal diameter (mm) 37.3 ± 8.5 32.4 ± 5.5 32.5 ± 4.9 0.01
RV mid-level diameter (mm) 30.0 ± 7.4 25.8 ± 5.1 26.7 ± 4.4 0.04
LVDD (mm) 66.2 ± 7.2 59.7 ± 4.2 49.3 ± 4.2  < 0.001
LVSD (mm) 59.2 ± 8.1 49.2 ± 4.5 33.3 ± 5.2  < 0.001
RWT 0.24 ± 0.04 0.27 ± 0.03 0.34 ± 0.04  < 0.001
Myocardial ass index (g/m2) 134.9 ± 32.3 113.2 ± 18.3 85.4 ± 15.3  < 0.001
LVDVi (ml/m2) 117.4 ± 40.4 85.4 ± 22.1 55.0 ± 16.4  < 0.001
LVSVi (ml/m2) 82.7 ± 32.7 47.2 ± 14.1 21.2 ± 7.4  < 0.001
LVEF (Simpson method) 0.31 ± 0.06 0.45 ± 0.03 0.62 ± 0.05  < 0.001
TAPSE 14.7 ± 3.1 18.0 ± 4.1 18.4 ± 2.8  < 0.001
RV S´ wave 9.3 ± 2.2 10.2 ± 2.9 12.2 ± 2.0  < 0.001
FAC 0.42 ± 0.15 0.52 ± 0.07 0.51 ± 0.08 0.004
Diastolic function
Normal N = 0 N = 3 (30%) N = 16 (53%)  < 0.001
Grade I N = 8 (25%) N = 6 (60%) N = 14 (47%)
Grade II N = 10 (31%) N = 1 (10%) N = 0
Grade III N = 6 (19%) N = 0 N = 0
Grade IV N = 7 (22%) N = 0 N = 0
Indeterminate N = 1 (3%) N = 0 N = 0
Septal e´ velocity (cm/s) 4.9 ± 1.9 6.0 ± 2.4 7.9 ± 1.9  < 0.001
Lateral e´velocity (cm/s) 5.0 ± 2.3 8.0 ± 2.9 9.8 ± 3.2  < 0.001
Average E/e´ 19.7 ± 12.4 10.2 ± 4.2 7.9 ± 2.0  < 0.001
Mitral regurgitation
Absent N = 5 (16%) N = 2 (20%) N = 23(77%)  < 0.001
Mild N = 11 (34%) N = 4 (40%) N = 7 (23%)
Moderate N = 7 (22%) N = 3 (30%) N = 0
Severe N = 9 (28%) N = 1 (10%) N = 0
Aorticregurgitation
Absent N = 26 (81%) N = 7 (70%) N = 26 0.28
Mild N = 6 (19%) N = 3 (30%) N = 2
Moderate N = 0 N = 0 N = 0
Severe N = 0 N = 0 N = 0
Tricuspidregurgitation
Absent N = 25 (78%) N = 10 (100%) N = 24 (86%) 0.06
Mild N = 2 (6%) N = 0 N = 4 (14%)
Moderate N = 1 (3%) N = 0 N = 0
Severe N = 4 (13%) N = 0 N = 0
PASP (mmHg) 51.4 ± 14.4 NA 27.5 ± 7.5 0.02
TR peak velocity (m/s) 3.36 ± 0.40 NA 2.36 ± 0.28 0.03
Diffuse hypokinesis N = 25 (78%) N = 3 (30%) N = 0 0.02
Inferior and lateral inferior walls akinesis N = 3 (9%) N = 3 (30%) N = 2 (7%)
Lateral inferior wall akinesis N = 1 (3%) N = 0 N = 0
Apical akinesis N = 2 (6%) N = 2 (20%) N = 0
Apical aneurysm N = 1 (3%) N = 2 (20%) N = 0
Apical thrombus N = 1 (3%) N = 0 N = 0 0.36
Pericardial effusion
Absent N = 30 (94%) N = 9 (90%) N = 27 (95%) 0.67
Mild N = 2 (6%) N = 1 (10%) N = 1 (5%)

Significant values are in bold.

*LVEF Left ventricular ejection fraction, SD Standard deviation, RA right atrium, RV right ventricle, LVDD Left ventricle diastolic diameter, LVSD Left ventricle systolic diameter, RWT relative wall thickness, LVDVi Left ventricle diastolic volume indexed, LVSDVi Left ventricle systolic volume indexed, TAPSE Tricuspid annular plane systolic excursion, FAC Right ventricle fractional area change, PASP Pulmonary artery systolic pressure, RT Tricuspid regurgitation.