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. 2022 Jul 18;7:80. doi: 10.1038/s41541-022-00502-z

Fig. 3. Antibody durability to variants of concern and seasonal strains of coronavirus post mRNA-1273 vaccination.

Fig. 3

A, B IgG titers as measured by EC50 against Wuhan RBD and spike proteins from the Beta (S. Africa), Gamma (Brazil), and Delta (India) VOCs (A), or against TT and the seasonal coronavirus strains 229E, HKU1 and OC43 (B). C gMFI of IgG against seasonal coronavirus strains at a serum dilution of 1:200. D Correlation of S2-specific IgG gMFI with IgG gMFI for OC43 but not HKU1. Graph shows the gMFI for each time point from day 0 to 92 at both 1:100 and 1:500 serum dilutions. E Nasal swabs were eluted in 500 ul of buffer, saliva was filtered, and both evaluated for IgG and IgA at a 1:2 dilution. Serum comparison was at 1:2000 dilution.