Table 3.
Voxel-based morphometry results of significant grey matter intensity reduction that correlates significantly with SPQ subdomain scores
| SPQ subdomains | Cluster size, voxels | MNI coordinates | T value | H | Regions | ||
|---|---|---|---|---|---|---|---|
| X | Y | Z | |||||
| Positive schizotypy | 3321 | 15 | 48 | 44 | 5.62 | Right | Superior frontal gyrus extending into medial frontal gyrus and anterior cingulate, and left medial and superior frontal gyrus |
| 1365 | – 26 | – 72 | – 56 | 5.53 | Left | Cerebellum lobules VIII, VIIb and Crus II | |
| 1429 | 18 | – 2 | 15 | 4.82 | Right | Caudate into thalamus | |
| 1175 | 40 | 26 | 2 | 4.32 | Right | Insular cortex into inferior frontal gyrus | |
| 744 | 15 | – 69 | – 27 | 3.85 | Right | Cerebellum lobule VI into left lobule VI and vermis of lobules IV and V | |
| 669 | 34 | 60 | – 14 | 4.61 | Right | Frontal orbital cortex into superior and middle frontal gyrus | |
| 673 | – 14 | 14 | 3 | 4.05 | Left | Caudate | |
| Disorganised thought disorder | 771 | – 27 | – 75 | – 54 | 4.38 | Left | Cerebellum lobule VIIb into lobules VIII and Crus II |
Results reported at cluster-level FWE-corrected p < .05 (cluster-forming threshold, p < .001)
Total intracranial volume was included as a nuisance variable in all analyses
H hemisphere, MNI Montreal Neurological Institute, SPQ the Schizotypal Personality Questionnaire