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. 2022 Jun 8;21(8):100255. doi: 10.1016/j.mcpro.2022.100255

Fig. 2.

Fig. 2

Quantitative analysis of the proteome in HCC tumors and NATs.A, principal component analysis (PCA) visualization of protein expression in HCC tumors and NATs. B, the volcano plot illustrating differentially expressed proteins (fold change>1.5, p < 0.05, by two-sided Student’s t test). C, the heatmap of the identified differentially expressed proteins. D and E, KEGG pathway enrichment analysis of the upregulated (D) and downregulated (E) proteins. The analysis was conducted by clusterProfiler (version: 3.16.0). See also supplemental Fig. S1 and supplemental Table S3. HCC, hepatocellular carcinoma; KEGG, Kyoto Encyclopedia of Genes and Genomes; NATs, normal adjacent tissues.