Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 5;13:913901. doi: 10.3389/fimmu.2022.913901

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Jiang, Zhang, Hu, Shang, Ming, Deng, Li, Ma, Liu and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Suppression of TLR4-mediated PI3K signaling by SP-D treatment in vivo. (A) Immunofluorescence with an antibody to p-PI3K in articular cartilage from the ACLT + MMx-induced OA rats with rhSP-D and TAK-242 treatment at 10 weeks post-surgery. (B) The ratios of immunoreactive cells were quantified in articular cartilage according to immunofluorescence. Data were expressed as mean ± SEM (n = 5). ^***P < 0.001 vs. the sham-operated group; ^###P < 0.001 vs. the OA-induction group; ^&&P < 0.01 vs. OA + rhSP-D group; ^@@@P < 0.001 vs. OA + TAK-242 group.