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. 2022 Jul 5;9:932498. doi: 10.3389/fmed.2022.932498

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Copyright © 2022 Wang and Birch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bland-Altman plots of difference of measurements between deep learning (DL) models and the reading center vs. their mean. (A) RP240 U-Net vs. manual grading; (B) RP240 hybrid model vs. manual grading; (C) RP340 U-Net vs. manual grading; and (D) RP340 hybrid model vs. manual grading. Coefficient of repeatability (CoR) is defined as 1.96 times the standard deviation of the difference. Dashed horizontal lines represent ±95% limit of agreement (mean ± CoR). Dotted horizontal lines represent the mean difference.