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. 2022 Apr 15;43(12):3694–3705. doi: 10.1002/hbm.25877

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Published 2022. This article is a U.S. Government work and is in the public domain in the USA. Human Brain Mapping published by Wiley Periodicals LLC.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Regions in which the annual percent change of cortical measures with age shows more rapid decline with comorbid severe‐PTSD and military mTBI. Plots of annual percent change in cortical thickness in the left rostral middle frontal gyrus and isthmus cingulate by age. Scatter plots are color coded with red triangles and blue circles corresponding to comorbid PTSD + mTBI and PTSD‐only, respectively. Linear models of annual percent change versus age within each group are corrected (p < .05). mTBI, mild traumatic brain injury; PTSD, posttraumatic stress disorder