Table 1.
Univariate analysis of risk factors for K. pneumoniae infection comparing carriers and patients who developed an infection within 30 days following colonization.
| Variable | Carriage (n = 107) | Infection (n = 58) | P-value a |
|---|---|---|---|
| Age mean (SD) | 65 (17.4) | 64.9 (17.8) | 0.74 |
| Male | 69 (65.1) | 36 (62.1) | 0.735 |
| Diabetes mellitus | 14 (13.9) | 4 (7.1) | 0.297 |
| Chronic renal disease | 11 (10.9) | 6 (10.7) | 1.000 |
| Solid organ transplantation | 4(4) | 4 (7) | 0.457 |
| Onco-hematological disease | 2(3.6) | 2(2) | 0.617 |
| Chemotherapy | 2 (2) | 1(1.8) | 1.000 |
| Carbapenems | 51 (50.5) | 28 (51.9) | 1.000 |
| Quinolones | 10 (9.9) | 2 (3.7) | 0.218 |
| Cephalosporins | 35 (34.7) | 21 (38.9) | 0.604 |
| Hospitalization within the last 2 months | 53 (52.5) | 34 (61.8) | 0.312 |
| Central venous catheter | 47(46.5) | 27 (48.2) | 0.869 |
| Gastrointestinal previous diseases | 12 (11.9) | 4 (7.1) | 0.419 |
| Abdominal surgery | 8 (7.9) | 6 (10.7) | 0.519 |
| Ventilation device | 51 (51) | 31 (55.4) | 0.620 |
| ICU/Semi-intensive care unit (vs. other medical wards) | 42 (72.4) | 51 (48.1) | 0.003 |
a
The P-values for each risk factor were calculated by Fisher’s exact test (categorical variables) or Mann–Whitney test (continuous variables).