Table 4.
Risk factors for AMI in APS by logistic models.
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| B | OR (95%CI) | p | B | OR (95%CI) | p | |
| APS with AMI | ||||||
| Age of onset | 0.011 | 1.011 (0.989, 1.034) | 0.341 | 0.007 | 1.007 (0.978, 1.038) | 0.638 |
| Male | 0.018 | 1.019 (0.440, 2.357) | 0.966 | −0.786 | 0.456 (0.160, 1.300) | 0.142 |
| Venous thrombosis | −1.512 | 0.221 (0.093, 0.522) | 0.001 | −2.247 | 0.106 (0.036, 0314) | <0.001 |
| Multiple organ thrombosis | 0.999 | 2.715 (1.230, 5.995) | 0.013 | 2.182 | 8.862 (1.817, 43.212) | 0.007 |
| Thrombotic events≥2 | 0.858 | 2.359 (1.076, 5.174) | 0.032 | −0.487 | 0.614 (0.142, 2.661) | 0.515 |
| Atherosclerosis | 1.656 | 5.236 (2.319, 11.824) | <0.001 | 1.686 | 5.397 (1.943, 14.994) | 0.001 |
| Chronic pulmonary disease | 1.631 | 5.111 (0.817, 31.977) | 0.081 | |||
| Smoking | 0.648 | 1.912 (0.810, 4.514) | 0.139 | |||
| Diabetes mellitus | 0.448 | 1.565 (0.589, 4.162) | 0.369 | |||
| Hypertension | 0.178 | 1.195 (0.542, 2.633) | 0.659 | |||
| Dyslipidemia | 0.588 | 1.800 (0.765, 4.238) | 0.179 | |||
| Chronic kidney disease | −1.187 | 0.305 (0.040, 2.354) | 0.255 | |||
| Hyperuricemia | −1.460 | 0.232 (0.030, 1.775) | 0.159 | |||
| White blood cell count > 9.5 ×109/L | 0.751 | 2.119 (0.864, 5.197) | 0.101 | |||
| Neutrophils > 6.3 ×109/L | 1.099 | 3.000 (1.328, 6.780) | 0.008 | 1.185 | 3.271 (1.268, 8.440) | 0.014 |
| Low HDL-c (<1.0 mmol/L for male; <1.2 mmol/L for female) | 0.011 | 1.011 (0.465, 2.201) | 0.977 | |||
| QTc>440 ms | 0.44 | 1.552 (0.681, 3.538) | 0.295 | |||
APS, antiphospholipid syndrome; AMI, acute myocardial infarction; HDL, high-density lipoprotein cholesterol. The bold values means significantly different (p <0.05).