. 2022 Jul 4;37(28):e216. doi: 10.3346/jkms.2022.37.e216

Table 2. Incidence and mortality cases and age-standardized rates of hepatobiliary and pancreatic cancers up to 2040.

Incidence											Mortality
Cancer site	Cases					ASR					Cancer site	Cases					ASR
	1999^a	2017^a	2040^b	AAPC		1999^a	2017^a	2040^b	AAPC			2002^a	2018^a	2040^b	AAPC		2002^a	2018^a	2040^b	AAPC
	1999^a	2017^a	2040^b	1999–2017^a	2018–2040^b	1999^a	2017^a	2040^b	1999–2017^a	2018–2040^b		2002^a	2018^a	2040^b	2002–2018^a	2019–2040^b	2002^a	2018^a	2040^b	2002–2018^a	2019–2040^b
Liver	11,920	12,080	13,089	0.1 (P = 0.500)	0.3 (P < 0.001)	25.8	13.5	8.5	−3.6 (P < 0.001)	−2.0 (P < 0.001)	Liver	9,637	7,769	6,037	−0.9 (P < 0.001)	−1.1 (P < 0.001)	18.7	8.0	3.2	−5.2 (P < 0.001)	−4.1 (P < 0.001)
GB	1,336	2,601	4,038	3.9 (P < 0.001)	1.9 (P < 0.001)	2.9	2.6	1.7	−0.5 (P = 0.171)	−1.6 (P < 0.001)	GB	1,240	1,775	2,391	2.4 (P < 0.001)	1.4 (P < 0.001)	2.4	1.6	0.9	−2.5 (P < 0.001)	−2.5 (P < 0.001)
BD (I+E)	2,385	5,958	7,964	5.7 (P < 0.001)	1.1 (P < 0.001)	5.1	5.9	3.2	1.1 (P = 0.084)	−2.7 (P < 0.001)	BD (I+E)	2,866	5,157	7,928	3.8 (P < 0.001)	2.0 (P < 0.001)	5.5	4.6	2.9	−1.0 (P < 0.001)	−2.1 (P < 0.001)
AoV	419	834	1,376	3.7 (P < 0.001)	2.3 (P < 0.001)	0.9	0.9	0.6	−0.6 (P = 0.217)	−1.2 (P < 0.001)	AoV	219	390	536	4.9 (P < 0.001)	1.5 (P < 0.001)	0.4	0.4	0.2	−0.2 (P = 0.654)	−2.6 (P < 0.001)
Pancreas	2,603	7,032	16,170	5.8 (P < 0.001)	3.6 (P < 0.001)	5.6	7.3	8.2	1.5 (P < 0.001)	0.5 (P < 0.001)	Pancreas	2,881	6,006	11,023	5.0 (P < 0.001)	2.8 (P < 0.001)	5.5	5.6	4.7	0.3 (P = 0.091)	−0.8 (P < 0.001)

ASR = age-standardized rates, AAPC = average annual percent change, GB = gallbladder, BD (I+E) = bile duct (intrahepatic+extrahepatic), AoV = ampulla of vater.

^aObserved values; ^bEstimated values.