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. 2021 Jan 5;16(3):677–682. doi: 10.1177/1932296820982584

Table 1.

Rebound Hyperglycemia Events in the HypoDE Study.

Preceding glucose nadir, mg/dL Blinded phase Follow-up phase Relative difference (%) P value
Frequency (per week) <70 2.39 (1.62) 2.06 (1.49) 14 .027
<55 1.04 (0.83) 0.75 (0.85) 28 .007
Duration (min) <70 215 (217) 188 (186) 12 .022
<55 205 (202) 198 (185) 3 .694
AUC >180 mg/dL (mg/dL × min) <70 15 476 (22 550) 11 961 (16 345) 23 .002
<55 15 437 (22 112) 12 432 (15 649) 19 .097

Note. RH events were defined as series of one or more sensor glucose values >180 mg/dL starting within two hours of a sensor glucose value <70 mg/dL or a subset of these events starting within two hours of a sensor glucose value <55 mg/dL. Results given as mean (SD).

Abbreviations: AUC, area under the (glucose concentration-time) curve; rtCGM, real-time continuous glucose monitoring.