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. 2022 Jul 5;13:922903. doi: 10.3389/fendo.2022.922903

Table 2.

Association between BMI (kg/m²) and total bone mineral density (g/cm2).

Model 1β (95% CI) P-value Model 2β (95% CI) P-value Model 3β (95% CI) P-value
Body mass index(kg/m²) 0.014 (0.013, 0.014) <0.001 0.006 (0.005, 0.006) <0.001 0.005 (0.004, 0.005) <0.001
Subgroup analysis stratified by gender
Males 0.015 (0.014, 0.015) <0.001 0.005 (0.005, 0.006) <0.001 0.005 (0.003, 0.006) <0.001
Females 0.013 (0.012, 0.014) <0.001 0.006 (0.005, 0.006) <0.001 0.004 (0.003, 0.006) <0.001
Subgroup analysis stratified by age
8–9 years (n = 1,223) 0.007 (0.006, 0.008) <0.001 0.007 (0.006, 0.008) <0.001 0.007 (0.006, 0.008) <0.001
10–11 years (n = 1,180) 0.007 (0.006, 0.008) <0.001 0.007 (0.006, 0.008) <0.001 0.007 (0.006, 0.008) <0.001
12–13 years (n = 944) 0.007 (0.006, 0.008) <0.001 0.006 (0.005, 0.007) <0.001 0.006 (0.004, 0.008) <0.001
14–15 years (n = 959) 0.007 (0.006, 0.008) <0.001 0.007 (0.006, 0.008) <0.001 0.006 (0.004, 0.007) <0.001
16–17 years (n = 961) 0.004 (0.003, 0.005) <0.001 0.004 (0.004, 0.005) <0.001 0.004 (0.003, 0.005) <0.001
18–19 years (n = 876) 0.004 (0.002, 0.005) <0.001 0.003 (0.002, 0.004) <0.001 0.004 (0.002, 0.006) <0.001
Subgroup analysis stratified by BMI
Q1, 18.1< 0.040 (0.036, 0.044) <0.001 0.022 (0.019, 0.025) <0.001 0.020 (0.016, 0.024) <0.001
Q2, 18.1-21.0 0.032 (0.024, 0.039) <0.001 0.014 (0.010, 0.019) <0.001 0.014 (0.009, 0.018) <0.001
Q3, 21.1–23.4 0.014 (0.008, 0.020) <0.001 0.007 (0.004, 0.011) <0.001 0.012 (0.004, 0.020) 0.002
Q4, >23.4 0.005 (0.004, 0.006) <0.001 0.001 (0.000, 0.002) <0.001 0.001 (0.001, 0.002) 0.042
P for trend <0.001 <0.001 <0.001

Model 1: No covariates were adjusted. Model 2: Age, gender, and race were adjusted. Model 3: Age, gender, race, education level, ratio of family income to poverty, activities status, diabetes status, ALT, ALP, AST, total calcium, total cholesterol, direct HDL cholesterol, LDL cholesterol, triglyceride, phosphorus, blood urea nitrogen, and serum glucose were adjusted. *In the subgroup analysis stratified by gender or race, the model is not adjusted for the stratification variable itself.