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. 2022 Jun 13;107(1):59–64. doi: 10.4269/ajtmh.22-0007

Table 2.

Proportion of participants with genetic antibiotic resistance determinants by antibiotic class by treatment group at 8 weeks from enrollment

Azithromycin (N = 49) Amoxicillin (N = 46) Odds ratio (95% CI) P value*
Macrolides 32 (65%) 30 (65%) 1.00 (0.43–2.34) 0.99
Beta-lactams 40 (82%) 38 (83%) 0.94 (0.33–2.68) 0.99
Fluoroquinolones 29 (59%) 22 (48%) 1.58 (0.70–3.56) 0.56
Sulfonamides 24 (49%) 14 (30%) 2.19 (0.95–5.09) 0.52
Trimethoprim 38 (78%) 26 (78%) 0.96 (0.36–2.53) 0.99
Tetracyclines 45 (92%) 40 (87%) 1.69 (0.44–6.41) 0.77
Rifampin 19 (39%) 15 (33%) 1.31 (0.56–3.04) 0.77
Aminoglycosides 31 (63%) 23 (50%) 1.72 (0.76–3.91) 0.52
Metronidazole 24 (49%) 29 (63%) 0.56 (0.25–1.28) 0.52
Aminocoumarins 10 (20%) 4 (9%) 2.69 (0.78–9.29) 0.52
Bacitracin 19 (39%) 12 (26%) 1.79 (0.75–4.30) 0.52
Fosfomycins 1 (2%) 2 (4%) 0.46 (0.04–5.23) 0.77
Elfamycins 34 (69%) 27 (59%) 1.60 (0.69–3.71) 0.56
Lipopeptides 2 (4%) 1 (2%) 1.91 (0.17–21.9) 0.80
Phenicol 8 (16%) 7 (15%) 1.09 (0.36–3.28) 0.99
Glycopeptides 0 0 NA NA
Cationic peptides 30 (61%) 22 (48%) 1.72 (0.76–3.89) 0.52
*

False discovery rate-adjusted P value.