Table 5.

Rate of complications at UC diagnosis (% and 95% confidence interval) stratified according to age at disease onset and length of diagnostic delay

Outcome	Short delay adult	Long delay adult Short delay pediatric	Long delay pediatric	p value short adult versus long adult	p value short ped. versus long ped	p value ped. versus adult
Colectomy	3.9 (2.4–5.4)	4.7 (1.9–7.6)	5.1 (1.4–8.7)	4.3 (0–10.2)	0.612	0.844	0.647
UC-related hospitalization	18.0 (15.0–20.9)	17.5 (12.4–22.7)	29.0 (21.4–36.6)	19.6 (8.1–31.0)	0.891	0.211	0.006
Colon dysplasia	0.9 (0.2–1.7)	0.5 (0–1.4)	1.4 (0–3.4)	0 (0–7.7)	0.513	0.412	0.732
Colorectal cancer	0.5 (0–1.0)	0.9 (0–2.3)	0 (0–2.7)	0 (0–7.7)	0.435	1.000	0.296
Any complication (colectomy, hospitalization, dysplasia, or CRC)	21.6 (18.4–24.8)	21.3 (15.8–26.9)	32.6 (24.8–40.4)	23.9 (11.6–36.2)	0.940	0.267	0.009
All EIMs	23.8 (20.5–27.1)	31.8 (25.5–38.0)	21.7 (14.9–28.6)	19.6 (8.1–31.0)	0.022	0.755	0.194
Oral aphthous ulcers	3.3 (1.9–4.7)	3.3 (0.9–5.7)	5.8 (1.9–9.7)	4.3 (0.0–10.2)	0.994	0.707	0.166
Erythema nodosum	2.4 (1.2–3.5)	2.8 (0.6–5.1)	0.7 (0.0–2.1)	0	0.697	0.563	0.099
Pyoderma gangrenosum	0.9 (0.2–1.7)	1.9 (0.1–3.7)	2.9 (0.1–5.7)	0	0.268	0.243	0.292
Arthritis/arthralgia	17.2 (14.2–20.1)	23.7 (18.0–29.4)	8.7 (4.0–13.4)	10.9 (1.9–19.9)	0.035	0.659	0.002
PSC	2.0 (0.9–3.1)	3.3 (0.9–5.7)	6.5 (2.4–10.6)	2.2 (0.0–6.4)	0.293	0.260	0.025
Uveitis/iritis	2.4 (1.2–3.5)	3.8 (1.2–6.4)	0.7 (0.0–2.1)	2.2 (0.0–6.4)	0.269	0.412	0.192
Ankylosing spondylitis/sacroiliitis	2.2 (1.1–3.3)	2.4 (0.3–4.4)	0.7 (0.0–2.1)	2.2 (0.0–6.4)	0.889	0.412	0.313