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. 2022 Apr 14;4(7):625–635. doi: 10.1016/j.cjco.2022.03.011

Table 3.

Breakfast and between-meal consumption and multivariable-adjusted hazard ratios (HRs) of hospitalization and/or mortality from coronary artery disease with 95% confidence intervals (CIs)

Breakfast
P
No Yes
Cases, n 40 706
Person-years 13,514.5 96,564.0
Adjusted for age and sex: HR (95% CI) 1.15 (0.83–1.60) 1.00 (Ref) 0.399
+ Demographic factors 1.13 (0.81–1.57) 1.00 (Ref) 0.473
 + Lifestyle and mental health factors 1.01 (0.72–1.40) 1.00 (Ref) 0.965
 + Dietary factors 1.00 (0.71–1.40) 1.00 (Ref) 0.993
Additional adjustment for potential mediators
 + Health conditions§ 1.01 (0.72–1.41) 1.00 (Ref) 0.971
 + BMI||
1.01 (0.72–1.41)
1.00 (Ref)
0.969
Between-meal consumption
P

No
Yes

Cases, n 87 659
Person-years 10,518.6 99,560.0
Adjusted for age and sex: HR (95% CI) 1.00 (Ref) 1.08 (0.87–1.35) 0.489
+ Demographic factors 1.00 (Ref) 1.08 (0.87–1.36) 0.477
 + Lifestyle and mental health factors 1.00 (Ref) 1.05 (0.84–1.32) 0.664
 + Dietary factors 1.00 (Ref) 1.03 (0.79–1.34) 0.834
Additional adjustment for potential mediators
 + Health conditions§ 1.00 (Ref) 1.03 (0.79–1.34) 0.831
 + BMI|| 1.00 (Ref) 1.03 (0.79–1.33) 0.853

Boldface indicates the main model being reported.

BMI, body mass index; Ref, referent.

In addition to age (years) and sex (male, female), this model is adjusted for the following baseline demographic factors: largest racial group (yes, no); marital status (married, not married); education (≤ secondary school graduation, > secondary school graduation, missing); immigrant (yes, no, missing); food secure (yes, no, missing); and household income (< $15,000, $15,000–$29,999, $30,000–$49,999, $50,000–$79,999, ≥ $80,000, missing).

In addition to age, sex, and baseline demographic factors, this model is further adjusted for the following baseline lifestyle and mental health factors: smoking (never, past, current, missing); alcohol intake (none- < 3 times per month, 1-3 times per week, 4+ times per week, missing); physical activity index (active, moderately active, inactive, missing); and life stress (not at all stressful, not very stressful, a bit stressful, quite a bit or extremely stressful, missing).

In addition to age, sex, baseline demographic, lifestyle, and mental health factors, this model is further adjusted for the following baseline dietary factors: consumption of sugar-sweetened beverages (yes, no); fruit and vegetable intake (times per day); eating frequency (times per day); sodium (mg per day), sugar (g per day); and energy intake (kcal per day). This is the main model reported for this analysis.

§

In addition to age, sex, and baseline demographic, lifestyle, mental health, and dietary factors, this model is further adjusted for the following baseline health conditions: high blood pressure (yes, no, missing); and diabetes (yes, no, missing).

||

In addition to age, sex, baseline demographic, lifestyle, mental health, and dietary factors, and baseline health conditions, this model is further adjusted for baseline BMI (kg/m2, < 18.5, 18.5-24.9, 25-29.9, ≥ 30).