Table 4. Two-Year Neurodevelopmental and Behavioral Outcomes Multivariable Models.
| Outcome | No. | Low behavioral risk with high medical risk | High behavioral risk with low medical risk | High behavioral risk with high medical risk | |||
|---|---|---|---|---|---|---|---|
| RR (95% CI) | aRR (95% CI)a | RR (95% CI) | aRR (95% CI)a | RR (95% CI) | aRR (95% CI)a | ||
| Bayley-III | |||||||
| No. | 220 | 76 | 76 | 106 | 106 | 38 | 38 |
| Cognitive composite <85 | 131 | 1.4 (0.9-2.2) | 1.2 (0.7-1.8) | 1.1 (0.7-1.8) | 1.2 (0.8-1.8) | 2.6 (1.8-3.8) | 2.7 (1.8-3.4) |
| Language composite <85 | 204 | 1.4 (1.1-1.9) | 1.3 (0.9-1.7) | 1.1 (0.8-1.5) | 1.0 (0.7-1.4) | 1.6 (1.2-2.3) | 1.3 (0.8-1.9) |
| Motor composite <85 | 102 | 3.4 (2.2-5.4) | 2.8 (1.8-3.9) | 1.8 (1.1-3.1) | 1.8 (1.1-2.7) | 5.1 (3.2. 8.0) | 4.1 (2.9-5.1) |
| Child Behavior Checklist | |||||||
| No. | 236 | 79 | 79 | 113 | 113 | 44 | 44 |
| Internalizing T score >63 | 43 | 1.0 (0.4-2.7) | 0.9 (0.3-2.4) | 1.9 (0.9-3.7) | 2.3 (1.1-4.5) | 2.2 (0.9-5.2) | 2.2 (0.6-6.4) |
| Externalizing T score >63 | 54 | 1.0 (0.4-2.2) | 0.8 (0.3-1.8) | 1.4 (0.7-2.5) | 1.4 (0.7-2.7) | 1.0 (0.4-2.7) | 0.8 (0.2-2.7) |
| Total problem score >63 | 53 | 1.4 (0.6-2.9) | 1.3 (0.5-2.9) | 1.9 (1.1-3.4) | 2.5 (1.2-4.4) | 1.8 (0.8-4.2) | 2.3 (0.7-5.4) |
Abbreviations: aRR, adjusted relative risk; Bayley-III, Bayley Scales of Infant and Toddler Development, third edition; RR, relative risk.
a
Adjusted for low socioeconomic status, minority race or ethnicity, maternal primary language, no partner, Brief Symptom Inventory average, postmenstrual age at birth, infant sex, and study site.