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Table 1. Baseline demographic characteristics and maximal cardiopulmonary exercise testing indices of patients with chronic heart failure of different severity according to peak VO2.

Demographic characteristics Group 1: ≤ 18.3 ml/kg/min Group 2: > 18.3 ml/kg/min
Number of patients (N) 23 21
Gender (males/females)  17/6   18/3 
Age (years)a 57 ± 11 54 ± 9
NYHA stage (class II/III)  17/6   17/4 
Ejection fraction (%) 30 (25-40) 35 (28-38)
Medication
 Diuretics [n (%)] 19 (83%) 10 (48%)*
 ACE inhibitors [n (%)] 11 (48%) 11 (52%)
 beta-blockers [n (%)] 23 (100%) 20 (95%)
 Aldosterone antagonists [n (%)] 17 (74%) 15 (71%)
Baseline cardiopulmonary exercise testing indices
 Peak VO2 (ml/kg/min)a 15.1 ± 2.8 22.1 ± 2.3*
 Predicted peak VO2 (%)a 55 ± 14 74 ± 11*
 Peak WR (watts)a 82 ± 33 122 ± 33*

ACE, angiotensin-converting-enzyme; NYHA, New York Heart Association; VO2, oxygen uptake; WR, work rate.

Values are expressed as a mean ± SD, b median (25th-75th percentiles).

Difference between the 2 severity groups for demographic characteristics and CPET parameters (* p < 0.05).