Table 1. Baseline demographic characteristics and maximal cardiopulmonary exercise testing indices of patients with chronic heart failure of different severity according to peak VO2.
Demographic characteristics | Group 1: ≤ 18.3 ml/kg/min | Group 2: > 18.3 ml/kg/min |
Number of patients (N) | 23 | 21 |
Gender (males/females) | 17/6 | 18/3 |
Age (years)a | 57 ± 11 | 54 ± 9 |
NYHA stage (class II/III) | 17/6 | 17/4 |
Ejection fraction (%) | 30 (25-40) | 35 (28-38) |
Medication | ||
Diuretics [n (%)] | 19 (83%) | 10 (48%)* |
ACE inhibitors [n (%)] | 11 (48%) | 11 (52%) |
beta-blockers [n (%)] | 23 (100%) | 20 (95%) |
Aldosterone antagonists [n (%)] | 17 (74%) | 15 (71%) |
Baseline cardiopulmonary exercise testing indices | ||
Peak VO2 (ml/kg/min)a | 15.1 ± 2.8 | 22.1 ± 2.3* |
Predicted peak VO2 (%)a | 55 ± 14 | 74 ± 11* |
Peak WR (watts)a | 82 ± 33 | 122 ± 33* |
ACE, angiotensin-converting-enzyme; NYHA, New York Heart Association; VO2, oxygen uptake; WR, work rate.
Values are expressed as a mean ± SD, b median (25th-75th percentiles).
Difference between the 2 severity groups for demographic characteristics and CPET parameters (* p < 0.05).