Supplementary Table 1. Acute response of the mobilization of endothelial cellular populations after maximal exercise in patients with chronic heart failure of high severity before and after a cardiac rehabilitation program.
Endothelial cellular populationsa | Before rehabilitation | After rehabilitation | p value of the acute response between CPETs | ||
Before CPET | After CPET | Before CPET | After CPET | ||
CD34+/CD45-/CD133+ | 54 (24-74) | 84 (52-102)# | 98 (76-131) | 154 (102-209)# | 0.004 |
CD34+/CD45-/CD133+/VEGFR2 | 2 (1-4) | 5 (3-8)# | 7 (4-9) | 15 (10-20)# | 0.001 |
CD34+/CD133+/VEGFR2 | 13 (9-16) | 13 (9-19) | 22 (17-36) | 27 (19-38)* | 0.165 |
CD34+/CD45-/CD133- | 186 (131-287) | 402 (204-544)# | 431 (301-618) | 738 (496-931)# | 0.073 |
CD34+/CD45-/CD133-/VEGFR2 | 1 (1-3) | 3 (3-5)# | 4 (3-8) | 10 (9-15)# | 0.003 |
High severity group: Peak VO2 ≤ 18.3 ml/kg/min; CPET, cardiopulmonary exercise testing.
a Values are expressed as “cells/106 enucleated cells” in median (25th-75th percentiles).
Significant difference in the acute mobilization of endothelial cellular populations after a symptom-limited maximal CPET (* p < 0.05; # p < 0.001). CPET, cardiopulmonary exercise test.