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. 2022 Jul 4;18(11):4301–4315. doi: 10.7150/ijbs.66224

Figure 1.

Figure 1

DLEU1 level and clinical relevance in CCA. (A) Volcano plot of differentially expressed lncRNAs in CCA from TCGA dataset (t-test). (B) Heatmap of the top 20 upregulated and downregulated lncRNAs with significant changes (t-test). (C) Detection of DLEU1 expression in CCA samples of TCGA database (t-test). (D) DLEU1 level was upregulated in CCA tissues (t-test). (E) DLEU1 level was higher at TNM III+IV stage than TNM I+II stage (t-test). (F) DLEU1 level was higher in patients with lymph node invasion (t-test). (G) Kaplan-Meier certified that worse OS occurred in patients with high DLEU1 expression (log rank test). (H) DLEU1 level and OS of patients were negatively correlated (linear regression). (I) ROC analysis was conducted to assess the prognostic correlation of DLEU1. ***p < 0.001.