Table 1.
Correlation between DLEU1 expression and clinicopathological characteristics of CCA patients
| Clinicopathological parameters | Total cases (n = 55) | DLEU1 expression | p-value | |
|---|---|---|---|---|
| Low (n = 26) | High (n = 29) | |||
| Age (years) | ||||
| < 60 | 15 | 9 | 6 | 0.364 |
| ≥ 60 | 40 | 17 | 23 | |
| Gender | ||||
| Male | 22 | 9 | 13 | 0.583 |
| Female | 33 | 17 | 16 | |
| Tumor location | ||||
| Intrahepatic | 24 | 13 | 11 | 0.422 |
| Extrahepatic | 31 | 13 | 18 | |
| Histological type | ||||
| Adenocarcinoma | 50 | 25 | 25 | 0.355 |
| Non-adenocarcinoma | 5 | 1 | 4 | |
| Differentiation grade | ||||
| Well/moderate | 26 | 15 | 11 | 0.181 |
| Poor/undifferentiated | 29 | 11 | 18 | |
| TNM stage | ||||
| I-II | 19 | 14 | 5 | 0.006** |
| III-IV | 36 | 12 | 24 | |
| Lymph node invasion | ||||
| Yes | 34 | 12 | 22 | 0.030* |
| No | 21 | 14 | 7 | |
| HBV infection | ||||
| Positive | 14 | 6 | 8 | 0.764 |
| Negative | 41 | 20 | 21 | |
| Serum CA19-9 level | ||||
| > 37 U/ml | 37 | 15 | 22 | 0.249 |
| ≤ 37 U/ml | 18 | 11 | 7 | |
| Serum CEA level | ||||
| > 5 ng/ml | 35 | 14 | 21 | 0.173 |
| ≤ 5 ng/ml | 20 | 12 | 8 | |
Note. *p < 0.05, **p < 0.01. Chi-square test. DLEU1, deleted in lymphocytic leukemia 1; CCA, cholangiocarcinoma.