Table 1.
Pathological characteristics of post-surgical HCC patients enrolled in Xiangya cohort
| Variables | High VIPR1 Group (n=54) | Low VIPR1 Group(n=53) | P value | |
|---|---|---|---|---|
| Age (years) | 55.3±1.4 | 51.6±1.4 | 0.067 | |
| Gender, n (%) | Male | 47 (87.0) | 42 (79.2) | 0.281 |
| Female | 7 (13.0) | 11 (20.8) | ||
| AFP, n(%) | ≥100ng/ml | 25 (46.3) | 30 (56.6) | 0.286 |
| <100ng/ml | 29 (53.7) | 23 (43.4) | ||
| Child-Pugh classification | A | 21 (38.9) | 16 (30.2) | 0.344 |
| B+C | 33 (61.1) | 37 (69.8) | ||
| Tumor multiplicity, n (%) | Solitary | 37 (68.5) | 25 (47.2) | *0.025 |
| Multiple | 17 (31.5) | 28 (52.8) | ||
| Tumor diameter, n (%) | ≥7cm | 18 (33.3) | 28 (52.8) | *0.042 |
| <7cm | 36 (66.7) | 25 (47.2) | ||
| Vascular invasion, n (%) | Y | 20 (37.0) | 38 (71.7) | ***0.0003 |
| N | 34 (63.0) | 15 (28.3) | ||
| Liver cirrhosis, n (%) | Y | 40 (74.1) | 36 (67.9) | 0.483 |
| N | 14 (25.9) | 17 (32.1) | ||
| Intrahepatic metastases, n(%) | Y | 7 (13.0) | 13 (24.5) | 0.125 |
| N | 47 (87.0) | 40 (75.5) | ||
| Distant metastases, n(%) | Y | 5 (9.3) | 15 (28.3) | *0.012 |
| N | 49 (90.7) | 38 (71.7) | ||
| TNM stage, n (%) | Ⅰ+Ⅱ | 32 (59.3) | 15 (28.3) | **0.0013 |
| Ⅲ+Ⅳ | 22 (40.7) | 38 (71.7) | ||
| Tumor differentiation, n (%) | Well | 4 (7.4) | 3 (5.7) | *0.025 |
| Moderately | 39 (72.2) | 26 (49.0) | ||
| Poorly | 11 (20.4) | 24 (45.3) |