Table 3.

Simulation results comparing one-step (os) and TML (tmle) estimators for the transported interventional indirect and direct effects with those for the nontransported interventional indirect and direct effects.

Effect type	Estimator			relse	relsd	relrmse	95%CI Cov
N = 10 000
Transported, indirect effect	os	0.0000	0.0030	0.9966	0.9760	0.9755	0.9420
Transported, indirect effect	tmle	0.0001	0.0065	0.9895	0.9778	0.9774	0.9400
Nontransported, indirect effect	os	0.0000	0.0022	0.9413	1.1722	1.1717	0.9420
Nontransported, indirect effect	tmle	0.0000	0.0035	0.9412	1.1690	1.1685	0.9420
Transported, direct effect	os	0.0005	0.0490	1.0200	0.9489	0.9488	0.9570
Transported, direct effect	tmle	0.0004	0.0415	1.0040	0.9610	0.9608	0.9530
Nontransported, direct effect	os	0.0013	0.1344	1.0178	1.1003	1.1074	0.9620
Nontransported, direct effect	tmle	0.0014	0.1397	1.0150	1.1033	1.1110	0.9640
N = 1000
Transported, indirect effect	os	0.0007	0.0229	0.9010	1.0200	1.0201	0.9041
Transported, indirect effect	tmle	0.0006	0.0200	0.8900	1.0209	1.0207	0.8988
Nontransported, indirect effect	os	0.0001	0.0045	0.9134	1.1626	1.1622	0.9340
Nontransported, indirect effect	tmle	0.0001	0.0042	0.9170	1.1495	1.1490	0.9300
Transported, direct effect	os	0.0014	0.0454	1.0200	0.8925	0.8921	0.9591
Transported, direct effect	tmle	0.0028	0.0880	0.9702	0.9309	0.9314	0.9414
Nontransported, direct effect	os	0.0025	0.0802	1.0212	1.0854	1.0876	0.9540
Nontransported, direct effect	tmle	0.0031	0.0968	1.0119	1.0949	1.0984	0.9540