Table 2.
Demographic and renal characteristics of 20 patients with Crohn’s disease referred for kidney biopsy
| Characteristic | Data |
|---|---|
| Patients — no | 20 |
| Male sex — no. (%) | 11 (55%) |
| Age at kidney biopsy — yr | 33.50±14.56 |
| Age distribution at kidney biopsy (yr) — no. (%) | |
| < 20 | 3 (15%) |
| 20–30 | 6 (30%) |
| 30–40 | 7 (35%) |
| 40–50 | 1 (5%) |
| 50–60 | 1 (5%) |
| ≥ 60 | 2 (10%) |
| Body mass index — Kg/m2 | 19.93±2.84 |
| Systolic blood pressure — mmHg | 110.60±13.17 |
| Diastolic blood pressure — mmHg | 71.50±7.16 |
| Serum albumin — g per L | 37.32±6.65 |
| Serum creatinine — umol per L | 115.589±113.71 |
| Blood urea nitrogen — mmol per L | 6.38±4.40 |
| eGFRa — ml per min per 1.73m2 | 99.77±44.30 |
| eGFRa category — no. (%) | |
| ≥ 90 ml per min per 1.73m2 | 14 (70%) |
| 60–89.9 ml per min per 1.73m2 | 3 (15%) |
| < 60 ml per min per 1.73m2 | 3 (15%) |
| Urine PH | 6.28±0.82 |
| Urinary protein excretion — g per 24 h | 0.84±1.25 |
| Degree of proteinuria (g per 24 h) — no. (%) | |
| ≤ 0.2 | 7 (35%) |
| > 0.2 to < 2.0 | 10 (50%) |
| ≥ 2.0 to < 3.5 | 1 (5%) |
| ≥ 3.5 to < 5.0 | 2 (10%) |
| ≥ 5.0 to 10.0 | 0 (0%) |
| ≥ 10.0 | 0 (0%) |
| Hematuria — no. (%) | 17 (85%) |
| Nephrolithiasis — no. (%) | 2 (10%) |
| Indication for kidney biopsy — no. (%) | |
| Nephrotic-range proteinuria | 2 (10%) |
| Subnephrotic proteinuria | 6 (30%) |
| Persistent hematuria and proteinuria | 5 (25%) |
| Isolated hematuria with acanthocytes | 5 (25%) |
| Impaired kidney function (serum creatinine > 1.5 mg/dl) | 2 (10%) |
| RAS inhibitors — no. (%) | 5 (25%) |
| Steroids to treat renal disease — no. (%) | 7 (35%) |
| Steroids intravenously — no. (%) | 6 (30%) |
| Steroids combined with immunosuppressive agents to treat renal disease — no. (%) | 1 (5%) |
a The estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration Formula (CKD-EPI)