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. 2022 Jul 19;228(1):68.e1–68.e12. doi: 10.1016/j.ajog.2022.07.014

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© 2022 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Similar Omicron-Spike specific antibody responses after boosting in pregnant, lactating, and non-pregnant

A–B, The dot plots show the peak IgG1, IgA, and IgM response against Omicron Spike in 5 pregnant individuals after receiving the second dose of a primary mRNA vaccine series (V2) and after the booster dose (V3). The lines connect samples from the same individual. Significance was determined by a Wilcoxon signed-rank test, asterisk represents P<.05 (ns). B, The dot plots show IgG1, IgA, and IgM levels against Omicron Spike in NP, P, and L individuals. The horizontal line represents the median for each group. Significance was determined by a Kruskal-Wallis test. No comparison was significant (ns). C, The dot plots show the NT50 against an Omicron Spike pseudovirus in NP, P, and L individuals. The horizontal line represents the median for each group. Significance was determined by a Kruskal-Wallis test. No comparison was significant (ns). D, The dot plots show the FcR-binding of antibodies against Omicron Spike in NP, P, and L individuals. The horizontal line represents the median for each group. Significance was determined by a Kruskal-Wallis test. No comparison was significant.

FcR, Fc receptor; IgA, immunoglobulin A; IgG1, immunoglobulin G1; IgM, immunoglobulin M; L, lactating; mRNA, messenger RNA; NP, nonpregnanct; ns, not significant; P, pregnant.

Atyeo. Antibody response to COVID-19 booster dose in pregnancy. Am J Obstet Gynecol 2023.