Table 6.
Inflammaging variables.
| Inflammaging variables | All subjects n = 106 Median (IQR) | Rheumatoid arthritis n = 52 Median (IQR) | Osteoarthritis n = 54 Median (IQR) | p- value |
|---|---|---|---|---|
| INF-γ pg/ml (n = 102) | 5.75 (13.23) | 5.75 (13.42) | 5.47 (13.22) | 0.976 |
| IL-10 pg/ml (n = 105) | 4.01 (4.42) | 4.07 (4.69) | 3.90 (4.48) | 0.992 |
| IL-1RA pg/ml | 24.72 (22.53) | 27.54 (27.35) | 22.29 (18.12) | 0.100 |
| IL-1 β pg/ml (n = 94) | 1.35 (2.37) | 1.71 (2.90) | 1.10 (1.93) | 0.061 |
| IL-6 pg/ml (n = 93) | 4.58 (14.41) | 4.65 (19.61) | 4.18 (13.71) | 0.320 |
| TNF-α pg/ml | 16.12 (11.71) | 17.48 (12.41) | 14.94 (10.80) | 0.499 |
| MMP-1 ng/ml | 8.43 (11.19) | 10.02 (9.71) | 6.72 (12.95) | 0.050 |
| MMP-2 ng/mla | 203.12 (50.42) | 204.62 (49.76) | 199.12 (51.47) | 0.764b |
| MMP-9 ng/ml | 242.06 (236.02) | 240.25 (279.88) | 244.43 (252.93) | 0.250 |
| TIMP-1 ng/mla | 77.47 (22.46) | 74.09 (25.06) | 80.71 (19.33) | 0.130b |
| TIMP-2 ng/mla | 47.12 (13.33) | 45.39 (14.14) | 48.79 (12.41) | 0.190b |
a
Average (Standard deviation);
b
t – Student; IL, Interleukins; IL-1RA, Interleukin - receptor antagonist 1; INF-γ, Interferon-gamma; IQR, Interquartile range; MMP, Metalloproteinases; TIMP, Tissue inhibitors of metalloproteinases; TNF-α, Tumor necrosis factor-alpha.