TABLE 2.
Variablea | Unadjusted HR (95% CI) | P | aHRb (95% CI) | P |
---|---|---|---|---|
Male sex | 1.71 (0.92–3.18) | 0.090 | 0.91 (0.43–1.91) | 0.80 |
E. coli | 0.26 (0.13–0.49) | <0.0001 | 0.38 (0.17–0.83) | 0.015 |
Nosocomial acquisition | 4.26 (2.28–7.94) | <0.0001 | 2.68 (1.32–5.42) | 0.006 |
Underlying disease | ||||
Liver cirrhosis | 2.98 (1.25–7.10) | 0.014 | 1.76 (0.58–5.37) | 0.32 |
ESRD | 4.47 (1.08–18.56) | 0.039 | 1.87 (0.28–12.57) | 0.52 |
Solid tumor, localized | 2.82 (1.49–5.35) | 0.002 | 1.96 (0.93–4.11) | 0.077 |
Metastatic solid tumor | 5.42 (2.83–10.39) | <0.0001 | 3.96 (1.28–12.24) | 0.017 |
Chemotherapy within 6 mo | 3.26 (1.59–6.67) | 0.001 | 1.27 (0.47–3.44) | 0.64 |
CCI | 1.35 (1.20–1.53) | <0.0001 | 1.03 (0.85–1.25) | 0.75 |
Source of infection | <0.0001 | 0.45 | ||
Urinary tract | Reference | Reference | ||
Biliary | 2.09 (0.75–5.81) | 0.16 | 1.42 (0.45–4.43) | 0.55 |
Other | 5.30 (2.70–10.44) | <0.0001 | 1.73 (0.74–4.05) | 0.21 |
Pitt bacteremia score | 1.29 (1.09–1.51) | 0.003 | 1.29 (1.06–1.56) | 0.012 |
Severe sepsis or septic shock | 3.78 (1.67–8.55) | 0.001 | 3.14 (1.30–7.59) | 0.011 |
Carbapenem | ||||
Other carbapenem | Reference | Reference | ||
Ertapenem | 0.59 (0.31–1.11) | 0.10 | 0.60 (0.29–1.22) | 0.16 |
ESRD, end-stage renal disease.
Variables with P values of <0.20 in univariate analyses were included in adjusted analyses.