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. 2022 Jun 16;66(7):e00287-22. doi: 10.1128/aac.00287-22

TABLE 2.

Thirty-day all-cause mortality risks in the propensity score-matched cohort

Variablea Unadjusted HR (95% CI) P aHRb (95% CI) P
Male sex 1.71 (0.92–3.18) 0.090 0.91 (0.43–1.91) 0.80
E. coli 0.26 (0.13–0.49) <0.0001 0.38 (0.17–0.83) 0.015
Nosocomial acquisition 4.26 (2.28–7.94) <0.0001 2.68 (1.32–5.42) 0.006
Underlying disease
 Liver cirrhosis 2.98 (1.25–7.10) 0.014 1.76 (0.58–5.37) 0.32
 ESRD 4.47 (1.08–18.56) 0.039 1.87 (0.28–12.57) 0.52
 Solid tumor, localized 2.82 (1.49–5.35) 0.002 1.96 (0.93–4.11) 0.077
 Metastatic solid tumor 5.42 (2.83–10.39) <0.0001 3.96 (1.28–12.24) 0.017
Chemotherapy within 6 mo 3.26 (1.59–6.67) 0.001 1.27 (0.47–3.44) 0.64
CCI 1.35 (1.20–1.53) <0.0001 1.03 (0.85–1.25) 0.75
Source of infection <0.0001 0.45
 Urinary tract Reference Reference
 Biliary 2.09 (0.75–5.81) 0.16 1.42 (0.45–4.43) 0.55
 Other 5.30 (2.70–10.44) <0.0001 1.73 (0.74–4.05) 0.21
Pitt bacteremia score 1.29 (1.09–1.51) 0.003 1.29 (1.06–1.56) 0.012
Severe sepsis or septic shock 3.78 (1.67–8.55) 0.001 3.14 (1.30–7.59) 0.011
Carbapenem
 Other carbapenem Reference Reference
 Ertapenem 0.59 (0.31–1.11) 0.10 0.60 (0.29–1.22) 0.16
a

ESRD, end-stage renal disease.

b

Variables with P values of <0.20 in univariate analyses were included in adjusted analyses.