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Iron-sulfur cluster binding residues of MjFsrI-N and ANME2c-FsrII-6D-N based on AlphaFold2 model prediction. Modeled structures of MjFsrI-N and ANME2c-FsrII-6D-N with docked [Fe4-S4] clusters from M. marburgensis F420-reducing [NiFe]-hydrogenase (Frh; PDB ID 3ZFS) (89). Cysteine residues of motifs A′, B′, and C are shown as described for Fig. 4.
