Skip to main content

View full-text article in PMC

. 2022 Jun 14;66(7):e00289-22. doi: 10.1128/aac.00289-22

TABLE 3.

Triazole MICs^a for efflux pump disruption strains made in CpMrr1 activating mutation containing background

Strain^b	MIC (μg/mL)
Strain^b	Fluconazole	Voriconazole	Isavuconazole	Itraconazole	Posaconazole
Cp29	64	0.5	0.125	0.125	0.125
Cp29 ^mdr1	32	0.5	0.125	0.125	0.06
Cp29 ^mdr1b	16	0.25	0.125	0.125	0.06
Cp29 ^cdr1b	16	0.25	0.06	0.125	0.06
Cp29 ^mdr1,mdr1b	16	0.25	0.125	0.125	0.06
Cp29 ^mdr1,cdr1b	16	0.25	0.06	0.125	0.06
Cp29 ^mdr1b,cdr1b	4	0.06	0.06	0.125	0.06
Cp29 ^{dr1,mdr1b,cdr1b}	4	0.06	0.06	0.125	0.06

^a

MICs obtained by broth microdilution assay as described in the CLSI document M27, 4th edition (32).

^b

Clinical isolate collection previously described by Berkow et al. (22).