Table S2. The effect of royal jelly and trans-10-hydroxy-2-decenoic acid (10H2DA) on the migration of HCT-116 and SW-480 cells. The analysis of wound space is shown as a relative level of changes of wound space compared to control cells (100%).
| HCT-116 | Relative wound space/% | ||
|---|---|---|---|
| t/h | |||
| γ(royal jelly)/ (µg/mL) | 0 | 12 | 24 |
| 0 | 100.00±0.01 | (52.4±0.9)a | (38.4±0.8)a |
| 10 | 100.00±0.01 | (77.2±1.1)ab | (60.1±1.2)ab |
| 100 | 100.00±0.01 | (88.1±0.7)ab | (77.6±0.4)ab |
| c(10H2DA)/µM | |||
| 0 | 100.00±0.01 | (52.4±0.9)a | (38.4±0.8)a |
| 10 | 100.00±0.01 | (80.6±1.2)ab | (75.0±0.8)ab |
| 100 | 100.00±0.01 | (92.5±1.0)ab | (80.8±0.8)ab |
| SW-480 | |||
| γ(royal jelly)/ (µg/mL) | |||
| 0 | 100.00±0.01 | (64.9±1.0)a | (51.4±0.5)a |
| 10 | 100.00±0.01 | (87.8±1.2)ab | (65.1±0.5)ab |
| 100 | 100.00±0.01 | (83.4±0.6)ab | (76.1±1.1)ab |
| c(10H2DA)/µM | |||
| 0 | 100.00±0.01 | (64.9±1.0)a | (51.4±0.5)ab |
| 10 | 100.00±0.01 | (8799±2.4)ab | (75.7±3.8)ab |
| 100 | 100.00±0.01 | (98.5±166)b | (85.2±2.4)ab |
Results are presented as mean value±S.E. of two independent experiments performed in four repeats. ap<0.05 is considered as statistically significant difference between treatments compared to control at the same time, and bp<0.05 is considered as statistically significant difference between concentrations in a treated group