Fig. 6.

Comparisons of the simulated and experimentally observed compartment signals. (A) The simulated (black) and observed (yellow and blue) compartment signals of chromosomes 10 of GM12878 (r = 0.80) and IMR90 (r = 0.78). The experimental data are lacking in the regions designated by gray bars. (B) Contour plot of the density of compartment signals of the whole genome on the plane of the simulated and observed signal values for GM12878 (r = 0.82) and IMR90 (r = 0.77). Density is the number of 100-kb chromatin segments in a bin of $0.1\times 0.1$ square on the plane. The experimental data are from ref. 5. Compartment signal is the first principal component (PC1) of the simulated or observed chromatin contact matrix.