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. 2022 Jul 13;42(28):5482–5498. doi: 10.1523/JNEUROSCI.0086-22.2022

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Copyright © 2022 Liu et al.

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Figure 7. — The relationship between Na_v1.2 and Na_v1.6 localizations and the myelination status of pyramidal neurons. A, B, Double immunostaining of V5-labeled Na_v1.2 with MBP (red) in unmyelinated neuron (A) and partially myelinated neuron (B). Scale bar, 10 µm. C, Double immunostaining of V5-labeled Na_v1.6 with MBP (left) and Caspr (right). Scale bar, 10 µm. D, The percentage of unmyelinated, partially myelinated, and myelinated neurons in Na_v1.2- or Na_v1.6-positive knock-in neurons. The number of cells analyzed, Na_v1.2, 60; Na_v1.6, 97. Movies 2, 3, 4 show 3D image details.