TABLE 3.
Linear regression analyses for the association between non-insulin-based IR indices and CAVI.
Variables | β (95%CI), CAVI |
|||
Model 1 | Model 2 | Model 3 | Model 4 | |
Per SD increase | ||||
TG/HDL-C | 0.100 (0.069–0.130)** | 0.055 (0.031–0.079)** | 0.050 (0.026–0.074)** | 0.001 (–0.053–0.056) |
TyG | 0.194 (0.164–0.224)** | 0.081(0.056–0.107)** | 0.068 (0.041–0.094)** | 0.092 (0.035–0.149)* |
METS-IR | 0.106 (0.075–0.136)** | 0.159(0.109–0.210)** | 0.135 (0.082–0.187)** | 0.121 (-0.031 to 0.272) |
TG/HDL-C | ||||
Q1 | Reference | Reference | Reference | Reference |
Q2 | 0.238 (0.152–0.323)** | 0.100 (0.036–0.164)* | 0.097 (0.033–0.161)* | 0.086 (0.018–0.154)* |
Q3 | 0.291(0.205–0.377)** | 0.112 (0.046–0.179)* | 0.107 (0.041–0.174)* | 0.085 (0.005–0.165)* |
Q4 | 0.442 (0.357–0.528)** | 0.223 (0.151–0.295)** | 0.206 (0.133–0.279)** | 0.155 (0.043–0.266)* |
TyG | ||||
Q1 | Reference | Reference | Reference | Reference |
Q2 | 0.303 (0.218–0.388) ** | 0.134 (0.070–0.197)** | 0.134 (0.070–0.198)** | 0.131 (0.065–0.196)* |
Q3 | 0.362 (0.277–0.447)** | 0.112 (0.046–0.179)* | 0.110 (0.043–0.176)* | 0.098 (0.024–0.171)* |
Q4 | 0.566 (0.481–0.650)** | 0.236 (0.165–0.306)** | 0.205 (0.132–0.278)** | 0.171 (0.071–0.271)* |
METS-IR | ||||
Q1 | Reference | Reference | Reference | Reference |
Q2 | 0.080 (-0.006 to 0.167) | 0.005 (-0.065 to 0.076) | -0.004 (-0.075 to 0.066) | -0.056 (-0.134 to 0.021) |
Q3 | 0.241 (0.155–0.327)** | 0.087 (0.001–0.174)* | 0.067 (-0.021 to 0.154) | -0.036 (-0.142 to 0.070) |
Q4 | 0.300 (0.213–0.386)** | 0.215 (0.097–0.334)** | 0.170 (0.049–0.219)* | -0.022 (-0.183 to 0.139) |
TG, triglyceride; HDL-C, high density lipoprotein cholesterol; TyG, triglyceride and glucose index; METS-IR, metabolic score for insulin resistance; CAVI, cardio-ankle vascular index; SD, standard deviation; CI, confidence interval.
Model 1: unadjusted.
Model 2: adjusted for age, sex, and BMI.
Model 3: adjusted for age, sex, BMI, smoking, drinking, prehypertension, diabetes mellitus, hyperuricemia, renal dysfunction, SBP, and DBP.
Model 4: adjusted for age, sex, BMI, smoking, drinking, prehypertension, diabetes mellitus, hyperuricemia, renal dysfunction, SBP, DBP, FPG, CREA, UA, TG, TC, HDL-C, and LDL-C.
*p < 0.05; **P < 0.001.