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. 2022 Jul 5;9:903307. doi: 10.3389/fcvm.2022.903307

TABLE 3.

Linear regression analyses for the association between non-insulin-based IR indices and CAVI.

Variables β (95%CI), CAVI
Model 1 Model 2 Model 3 Model 4
Per SD increase
TG/HDL-C 0.100 (0.069–0.130)** 0.055 (0.031–0.079)** 0.050 (0.026–0.074)** 0.001 (–0.053–0.056)
TyG 0.194 (0.164–0.224)** 0.081(0.056–0.107)** 0.068 (0.041–0.094)** 0.092 (0.035–0.149)*
METS-IR 0.106 (0.075–0.136)** 0.159(0.109–0.210)** 0.135 (0.082–0.187)** 0.121 (-0.031 to 0.272)
TG/HDL-C
Q1 Reference Reference Reference Reference
Q2 0.238 (0.152–0.323)** 0.100 (0.036–0.164)* 0.097 (0.033–0.161)* 0.086 (0.018–0.154)*
Q3 0.291(0.205–0.377)** 0.112 (0.046–0.179)* 0.107 (0.041–0.174)* 0.085 (0.005–0.165)*
Q4 0.442 (0.357–0.528)** 0.223 (0.151–0.295)** 0.206 (0.133–0.279)** 0.155 (0.043–0.266)*
TyG
Q1 Reference Reference Reference Reference
Q2 0.303 (0.218–0.388) ** 0.134 (0.070–0.197)** 0.134 (0.070–0.198)** 0.131 (0.065–0.196)*
Q3 0.362 (0.277–0.447)** 0.112 (0.046–0.179)* 0.110 (0.043–0.176)* 0.098 (0.024–0.171)*
Q4 0.566 (0.481–0.650)** 0.236 (0.165–0.306)** 0.205 (0.132–0.278)** 0.171 (0.071–0.271)*
METS-IR
Q1 Reference Reference Reference Reference
Q2 0.080 (-0.006 to 0.167) 0.005 (-0.065 to 0.076) -0.004 (-0.075 to 0.066) -0.056 (-0.134 to 0.021)
Q3 0.241 (0.155–0.327)** 0.087 (0.001–0.174)* 0.067 (-0.021 to 0.154) -0.036 (-0.142 to 0.070)
Q4 0.300 (0.213–0.386)** 0.215 (0.097–0.334)** 0.170 (0.049–0.219)* -0.022 (-0.183 to 0.139)

TG, triglyceride; HDL-C, high density lipoprotein cholesterol; TyG, triglyceride and glucose index; METS-IR, metabolic score for insulin resistance; CAVI, cardio-ankle vascular index; SD, standard deviation; CI, confidence interval.

Model 1: unadjusted.

Model 2: adjusted for age, sex, and BMI.

Model 3: adjusted for age, sex, BMI, smoking, drinking, prehypertension, diabetes mellitus, hyperuricemia, renal dysfunction, SBP, and DBP.

Model 4: adjusted for age, sex, BMI, smoking, drinking, prehypertension, diabetes mellitus, hyperuricemia, renal dysfunction, SBP, DBP, FPG, CREA, UA, TG, TC, HDL-C, and LDL-C.

*p < 0.05; **P < 0.001.