Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 19;79(8):432. doi: 10.1007/s00018-022-04460-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — Increased capillary lumen area associates with lower number of age-associated brain protein aggregates in the HIF-P4H-2 deficient mice. A The total capillary lumen area, the average size of a capillary lumen and the number of individual capillaries analyzed in senescent age-matched wild-type (WT) and Hif-p4h-2^gt/gt (gt/gt) brain sections with GLUT1 staining. In the histological pictures the brain regions of the enlarged pictures are shown in the inset by a red square. Asterisks indicate examples of capillaries. B Correlation of the number of brain protein aggregates with the total capillary lumen area. Data are means ± SEM. *P < 0.05 in T-test. n = 6 WT, 6 gt/gt. agg. Aggregates, HPF high-powered field