Table 2.
Characteristics of patients.
| n | Range, % | |
|---|---|---|
| Sex | ||
| M | 420 | 81.9 |
| F | 93 | 18.1 |
| Age (median) | 54 | 24–88 |
| Complete blood count | ||
| Hemoglobin (g/dl, median) | 12.2 | 3.4–16.8 |
| White blood cell count (×109/l, median) | 2.8 | 0.6–77.88 |
| Absolute neutrophil count (×109/l, median) | 0.864 | 0.25–9.512 |
| Absolute lymphocyte count (×109/l, median) | 1.639 | 0.15–15.042 |
| Circulating hairy cells | 138 | 26.8 |
| Platelet count (×109/l, median) | 78 | 1–397 |
| Bone marrow data | ||
| Bone marrow total cellularity (%) | 55 | 8–100 |
| Bone marrow leukemic cellularity (%) | 80 | 8–100 |
| BRAF-V600E mutation (available in 136 patients) | 136 | 100 |
| Onset characteristics | ||
| Splenomegaly | 241 | 46.9 |
| Hepatomegaly | 42 | 8.2 |
| Lymphadenomegaly | 30 | 5.8 |
| ECOG | ||
| 0 | 436 | 84.9 |
| 1 | 71 | 13.9 |
| 2 | 6 | 1.2 |
| Comorbidity | ||
| Infection | 37 | 7.2 |
| Cardiovascular disease | 29 | 5.6 |
| Previous cancer | 27 | 5.2 |
| Diabetes | 27 | 5.2 |
| Hepatic disease | 18 | 3.5 |
| CODP | 16 | 3.1 |
| Chronic kidney disease | 3 | 0.6 |