Table 6.
Univariate analysis for characteristics associated with CR compared to PR.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p value | OR | 95% CI | p value | |
| Age | 0.99 | 0.97, 1.01 | 0.26 | |||
| Year of diagnosis | ||||||
| 1990–2009 | – | – | ||||
| 2010–2019 | 1.11 | 0.70, 1.74 | 0.66 | |||
| Sex | ||||||
| M | – | – | ||||
| F | 0.72 | 0.42, 1.27 | 0.25 | |||
| ECOG | ||||||
| 0 | – | – | ||||
| 1–2 | 2.13 | 0.99, 5.30 | 0.074 | |||
| Hb (g/dl) | 1.09 | 0.99, 1.19 | 0.072 | 1.12 | 1.02, 1.22 | 0.021 |
| Plts | 1 | 1.00, 1.00 | 0.32 | |||
| Wbc | 1 | 1.00, 1.00 | 0.36 | |||
| Circulating hairy cells | ||||||
| Yes | – | – | ||||
| No | 3.66 | 1.34, 12.9 | 0.021 | 3.72 | 1.35, 13.2 | 0.02 |
| Time to treatment | 1 | 0.99, 1.01 | 0.5 | |||
| Route of administration | ||||||
| IV | – | – | ||||
| SC | 1.2 | 0.74, 1.97 | 0.47 | |||
| CODP | ||||||
| No vs Yes | 0.26 | 0.01, 1.31 | 0.19 | |||
| Diabetes | ||||||
| No vs Yes | 0.65 | 0.18, 1.75 | 0.43 | |||
| Hepatic disease | ||||||
| No vs Yes | 2.24 | 0.66, 6.90 | 0.17 | |||
| Cardiovascular disease | ||||||
| No vs Yes | 1.21 | 0.43, 3.02 | 0.69 | |||
| Previous cancer | ||||||
| No vs Yes | 0.75 | 0.21, 2.07 | 0.61 | |||
| Splenomegaly at onset | ||||||
| No vs Yes | 0.93 | 0.58, 1.48 | 0.76 | |||
| Lymphoadenomegaly at onset | ||||||
| No vs Yes | 2.11 | 0.86, 4.93 | 0.089 | |||
| Hepatomegaly at onset | ||||||
| No vs Yes | 1.46 | 0.66, 3.01 | 0.32 | |||
OR odds ratio, CI confidence interval.
Bold values refer to statistically significant results.