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. 2022 Jul 19;12:12313. doi: 10.1038/s41598-022-16567-8

Table 1.

Descriptive statistics for included studies.

Descriptive statistics by study Mean
Age (years) 13.56 ± 1.79
Proportion of male/female participants 52.60%
Treatment duration (weeks) 12.76 ± 11.35
Race
White 69.04%
Black 18.41%
Asian 6.65%
Indigenous 10.35%
Other/multiple 10.94%
Descriptive statistics by effect size n %
Decade
1990s 4 0.72
2000s 212 37.99
2010s 272 48.75
2020s 70 12.54
SITB outcome
Suicide ideation 191 34.23
Suicide attempt 81 14.52
Suicide death 41 7.35
Self-harm 44 7.88
NSSI 37 6.63
Hospitalization 9 1.60
Other/combined SITBs 155 27.78
Specific intervention type
Medication only 370 66.31
Psychotherapy and medication combined 68 12.19
CT/CBT 47 8.42
Mixed psychotherapy modalities 12 2.15
Psychoeducation 8 1.43
DBT 11 1.97
Family based therapy 7 1.26
Parenting skills training 5 0.90
HIV prevention 4 0.72
Safety planning/means restriction 4 0.72
Motivational interviewing 4 0.72
Mentalization-based therapy 3 0.53
Community mentorship program 2 0.36
Partial hospitalization 2 0.36
Psychoanalysis/insight-based therapy 2 0.36
Acute psychiatric services 1 0.18
Bullying intervention 1 0.18
Case management services 1 0.18
Interpersonal psychotherapy 1 0.18
Mindfulness/meditation 1 0.18
Prevention program 1 0.18
Protective factor approach 1 0.18
Social skills training 1 0.18
Trigeminal nerve stimulation 1 0.18
Control group type
No treatment 16 2.87
Placebo 284 50.90
Active treatment 258 46.24
Medication class
Selective serotonin reuptake inhibitor 109 29.46
Atypical antipsychotic 93 25.14
Selective norepinephrine reuptake inhibitor 79 21.35
Atypical antidepressant 30 8.11
Alpha-2 adrenergic agonist 14 3.78
Stimulants 11 2.97
Hypnotic 9 2.43
Combination medication 6 1.62
GirK inhibitor 6 1.62
Mood stabilizer 5 1.35
Tricyclic antidepressant 4 1.08
Noradrenergic and specific serotonergic antidepressant 2 0.54
Tricyclic antidepressants 4 1.08
Sample severity
General 42 7.53
Clinical 471 84.41
SITB 45 8.06
Age group
Children only 37 6.63
Children and adolescents 518 92.83
Intervention target type
SITBs 94 16.85
Psychopathology 443 79.39
Other 21 3.76
Treatment components
Individual only 422 75.63
Family only 11 1.97
Group only 13 2.33
Individual and family 87 15.59
Individual, family, and group 15 2.69
School-based 10 1.79
Individual skills training provided 145 77.13
Designed or adapted for adolescents 128 85.33
Study quality
Weak 252 45.16
Moderate 284 50.90
Strong 22 3.94
Therapist training and adherence
Therapist adherence check 151 27.06
Therapist pre-treatment training 154 27.60