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. 2022 Jul 19;12(7):110. doi: 10.1038/s41408-022-00704-7

Fig. 2. BRD9 degrader treatment leads to inhibition of AML cell line proliferation.

Fig. 2

AE Proliferation assays: AML cell lines treated with QA-68 or dBRD9-A. 6-day assay. Proliferation studies shown are representative of independent studies performed at least twice for which similar results were observed. F Effects of QA-68 (upper panel) and dBRD9-A (lower panel) on BRD9 expression in QA-68-sensitive and –insensitive AML cell lines. 24-hour assay. G Effects of QA-68 on SKM-1 cell differentiation. 4-day assay. H Effects of QA-68 on SKM-1 cell cycle progression. 6-day assay.