Table 3.

Univariate and multivariable analyses of OS and DFS in GC patients (*P < 0.05).

Variable	OS			DFS
	Univariate analysis	Multivariable analysis		Univariate analysis	Multivariable analysis
	P > |z|	P > |z|	HR (95% CI)	P > |z|	P > |z|	HR (95% CI)
HDAC4 expression
Low (n = 28) vs. high (n = 82)	0.001*	0.037*	2.419 (1.057–5.536)	0.001*	0.033*	2.473 (1.075–5.694)
Gender
Male (n = 69) vs. female (n = 41)	0.107			0.130
Age (years)
<63 (n = 57) vs. ≥54 (n = 53)	0.244			0.270
Tumour differentiation
Poor (n = 43) vs. well/moderate (n = 67)	0.016*			0.017*
Tumour diameter (cm)
<5 (n = 60) vs. ≥5 (n = 50)	0.090			0.106
CEA level (ng/ml)
≤2 (n = 49) vs. >2 (n = 61)	0.524			0.511
Depth of invasion
T1 + T2 (n = 40) vs. T3 + T4 (n = 70)	<0.001*	0.002*	4.024 (1.663–9.734)	<0.001*	0.001*	4.265 (1.758–10.345)
Lymph node metastasis
Negative (n = 59) vs. positive (n = 51)	<0.001*	<0.001*	7.527 (3.609–15.698)	<0.001*	<0.001*	8.074 (3.842–16.965)
Tumour location
Up (n = 18) vs. down/middle (n = 92)	0.879			0.858