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. Author manuscript; available in PMC: 2023 Jul 25.
Published in final edited form as: Angew Chem Int Ed Engl. 2022 Jun 13;61(30):e202201843. doi: 10.1002/anie.202201843

Figure 2.

Figure 2.

Optical and photoacoustic limits of detection for C2A with recombinant gingipain (RgpB). (A) Absorbance spectra of C2A incubated with 0 – 25 nM RgpB after 90 minutes. (B) Fluorescence spectra (ex: 600 nm, em: 700 nm) of the samples after 90 minutes. (C) Fluorescence limit of detection for RgpB via fluorescence area scan (ex: 625, em: 700 nm, LOD = 1.1 nM, linear range: 0 – 5 nM, R2 = 0.93, n = 2, error = SEM). (D) Photoacoustic-ultrasound image with quantitated intensities for RgpB from 0 – 25 nM (ex: 680 nm, LOD = 15 nM, inset = raw photoacoustic ultrasound image, Bu. = buffer).