Table 2:
Clinical characteristics non-upstaged patients vs. upstaged
| Patient Clinical Characteristics | Non-upstaged (N = 71) | Upstaged (N = 23) | P-value |
|---|---|---|---|
| Mean BMI (SD) | 30.4 | 26.9 | 0.01 |
| Mean CEA (SD) | 1.8 (2.6) | 2.2 (2.2) | 0.47 |
| Imaging modality | |||
| ERUS | 34 | 9 | 0.75 |
| MRI | 30 | 11 | |
| Both | 7 | 3 | |
| Tumor characteristics | |||
| Mean diameter cm (SD) | 2.4 (2.4) | 3.1 (1.6) | 0.23 |
| Mean length cm (SD) | 2.2 (1.6) | 2.9 (1.2) | 0.27 |
| Location | |||
| Unknown | 18 | 3 | 0.55 |
| Low rectum | 15 | 6 | |
| Mid rectum | 26 | 11 | |
| Upper rectum | 12 | 3 | |
| Clinical T-stage | 0.13 | ||
| T1 | 31 | 6 | |
| T2 | 40 | 17 | |
| Mean distance from anal verge cm (SD) | 8.6 (3.4) | 7.7 (3.1) | 0.62 |
| Mean distance from anal sphincter cm (SD) | 3.7 (3.2) | 2.6 (2.5) | 0.77 |
| Mean time from diagnosis to surgery - days (SD) | 54 (49) | 51 (30) | 0.02 |
| Operation type | |||
| LAR | 58 | 17 | 0.07 |
| APR | 4 | 4 | |
| Total Proctocolectomy | 0 | 1 | |
| Unknown | 9 | 1 | |
| Positive margin (proximal, distal or circumferential) | 0.58 | ||
| Yes | 1 | 1 | |
| No | 64 | 21 | |
| Could not be assessed | 6 | 1 | |
| Mean lymph nodes harvested (SD) | 16.5 | 17.7 | |
| Degree of differentiation | |||
| Well differentiated | 10 | 1 | 0.13 |
| Moderately differentiated | 30 | 16 | |
| Poorly differentiated | 2 | 0 | |
| Undifferentiated | 0 | 0 | |
| Not recorded | 29 | 6 | |
| Quality of TME | 0.07 | ||
| Complete | 48 | 14 | |
| Near complete | 1 | 1 | |
| Incomplete | 0 | 2 | |
| Not recorded | 22 | 6 |