Table 3.
Associations between biomarkers and postoperative complications
| Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| Unadjusted HR (95% CI) | P-value | Harrell C-index |
Adjusted HR (95% CI) | P-value | |
| HRG | 0.92 (0.88–0.96) | < 0.001 | 0.65 | 0.94 (0.90–0.99) | 0.014 |
| WBC/1000 | 0.98 (0.90–1.06) | 0.554 | 0.50 | 0.97 (0.89–1.06) | 0.484 |
| CRP | 1.08 (1.003–1.16) | 0.042 | 0.59 | 1.03 (0.96–1.11) | 0.453 |
| PCT | 1.06 (1.01–1.11) | 0.019 | 0.73 | 1.03 (0.98–1.09) | 0.284 |
| P-SEP/100 | 1.18 (1.12–1.24) | < 0.001 | 0.73 | 1.13 (1.06–1.20) | < 0.001 |
HR hazard ratio, Adjusted HR hazard ratio adjusted for age, presence of preoperative cardiovascular comorbidities, American Society Anesthesiologists Physical Status Classification, operative time, and volume of intraoperative bleeding, CRP C-reactive protein, HRG histidine-rich glycoprotein, P-SEP presepsin, PCT procalcitonin, WBC white blood cell