Table 3.
Multivariable regression analysis of risk factors for overall and major PPC
| Variable | Overall PPCs | Major PPCs | ||
|---|---|---|---|---|
|
|
|
|||
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age | 0.97 (0.86–1.09) | 0.567 | 1.09 (0.9–1.33) | 0.391 |
|
| ||||
| Male sex | 1.31 (0.33–5.29) | 0.7 | 15.49 (1.19–200.97) | 0.036 |
|
| ||||
| Current or former smoking | 1.9 (0.45–8) | 0.384 | 0.69 (0.07–6.38) | 0.74 |
|
| ||||
| ASA ≥ 3 | 2.53 (1.03–6.2) | 0.043 | 0.62 (0.15–2.55) | 0.503 |
|
| ||||
| Serum albumin (g/dL) | 0.56 (0.18–1.76) | 0.321 | 0.62 (0.12–3.14) | 0.567 |
|
| ||||
| Percentage predicted DL CO | 0.99 (0.97–1.01) | 0.29 | 0.98 (0.95–1.01) | 0.218 |
|
| ||||
| ILA | ||||
|
| ||||
| No ILA | Reference | |||
|
| ||||
| Nonfibrotic ILA | 1.37 (0.55–3.38) | 0.5 | 0.34 (0.06–1.99) | 0.23 |
|
| ||||
| Fibrotic ILA | 4.84 (1.35–17.38) | 0.016 | 8.72 (1.71–44.38) | 0.009 |
|
| ||||
| Emphysema | 1.13 (0.43–3) | 0.805 | 0.43 (0.09–1.99) | 0.278 |
|
| ||||
| Nonadenocarcinoma | 1.3 (0.54–3.13) | 0.552 | 4.13 (0.92–18.59) | 0.064 |
|
| ||||
| ≥ Lobectomy | 10.39 (2.77–39.04) | 0.001 | 9.66 (1.01–92.42) | 0.049 |
ASA, American Society of Anesthesiologists; CI, confidence interval; DLCO, diffusing capacity of the lung for carbon monoxide; ILA, interstitial lung abnormality; OR, odds ratio; PPCs, postoperative pulmonary complications.