Table 2.

Clinical Profile of 20 Patients With Periprosthetic Joint Infection Secondary to Corynebacterium spp.

Patient	Age at PJI/Gender	BMI	Comorbidities	Primary Arthroplasty	Revision	Micro at Prior PJIa	Prior Suppressive ABX	Time to PJI, mob	Temporal Classification	Micro at Current PJI	No. of Specimens With Growth	Specimen Type
1	79/M	25.8	CAD, chronic LLE ulcer	L knee	…	…	…	25.7	Late	C. striatum	≥2	SF/IO
2	91/M	32.2	CKD, obesity	L knee	Aseptic	…	MIN	51.6	Late	C. striatum	≥2	IO
3	60/M	32.3	DM, obesity	R knee	…	…	…	0.5	Early	C. striatum	≥2	IO
4	82/F	36	CAD, DM, CHF, PAD, CKD, obesity, R leg HL, R leg radiation therapy	R knee	Aseptic	…	…	94.3	Late	C. striatum	≥2	SF
5	40/F	34.6	Teratologic right hip dislocation, obesity	R hip	Aseptic	…	…	0.6	Early	C. amycolatum	≥2	SF/IO
6	59/M	62	CHF, obesity, RLE lymphedema	R knee	Septic-DAIR	S. marcescens	SXT	36.5	Late	C. jeikeium	1	IO
7	75/M	36.4	CAD, obesity	L knee	Septic-2-stage	CoNS	…	19.4	Late	C. striatum	≥2	SF/IO
8	58/F	29.8	CKD	R knee	Septic-DAIR	Negative	MIN	11.8	Delayed	C. striatum	≥2	SF/IO
9	65/F	37	Liver cirrhosis, DM, CHF, chronic RLE ulcer, CKD, obesity	L knee	…	…	…	33.4	Late	C. striatum	1	SFc
10	50/M	21.9	Klipperl-trenaunay syndrome, asplenia	L knee	…	…	…	30.0	Late	C. jeikeium	1	SF
11	59/M	42.4	CAD, DM, CHF, chronic LLE ulcer, CKD, obesity	L knee	Septic-DAIR	MSSA	LEX	31.8	Late	C. striatum	≥2	SF/IO
12	63/F	20	RA, Crohn’s disease, immunosuppressive medications	R hip	Septic-DAIR	P. mirabilis	…	30.4	Late	C. striatum	≥2	IO
13	55/F	25.5	RA, Marfan syndrome, immunosuppressive medications	R knee	…	…	…	12.2	Late	C. jeikeium	1	IOd
14	69/M	32	Obesity	L hip	Aseptic	…	…	6.4	Delayed	C. amycolatum	≥2	IO
15	68/F	33.5	RA, Sjogren syndrome, obesity	R knee	…	…	…	13.3	Late	C. jeikeium	1	IOd
16	57/M	31.3	DM, CKD, COPD, obesity, cerebellar ataxia, developmental delay	L hip	…	…	…	9.7	Delayed	C. striatum	≥2	SF/IO
17	85/M	27.9	CAD, DM, metastatic colon CA	R knee	…	…	…	8.2	Delayed	C. striatum	≥2	SF/IO
18	69/F	26.1	PAD, CKD, localized bladder CA, radiation to pelvis	R hip	…	…	…	47.2	Late	C. striatum	≥2	IO
19	65/M	42.8	DM, CIDP, immunosuppressive medications, obesity	R knee	Septic-DAIR	C. striatum	…	20.7	Late	C. striatum	≥2	SF/IO
20	51/F	NR	Breast CA	R knee	…	…	…	5.2	Delayed	C. striatum	1	SF

Abbreviations: ABX, antibiotics; BMI, body mass index; CA, cancer; CAD, coronary artery disease; CHF, congestive heart failure; CIDP, chronic inflammatory demyelinating polyneuropathy; CKD, chronic kidney disease; CoNS, coagulase-negative staphylococci; DAIR, debridement, antibiotic, and implant retention; DM, diabetes mellitus; F, female; HL, Hodgkin’s lymphoma; IO, intraoperative; L, left; LEX, cephalexin; LLE, left lower extremity; M, male; MIN, minocycline; MSSA, methicillin-susceptible Staphylococcus aureus; NR, not reported; PAD, peripheral arterial disease; R, right; RA, rheumatoid arthritis; RLE, right lower extremity; SF, synovial fluid; SXT, trimethoprim-sulfamethoxazole.

^aStands for prior PJI episodes affecting the same joint as current PJI.

^bTime from last arthroplasty surgery to current PJI.

^cGrowth from broth only.

^dProsthesis sonicate fluid culture.